Publikationen
2023
- Examination on the Occurrence of Coinfections in Diagnostic Transmittals in Cases of Stilbirth, Mummification, Embryonic Death, and Infertility (SMEDI) Syndrome in Germany.
Eddicks M., Gründl J., Seifert A., Eddicks L., Reese S., Tabeling R., Swam H., Strutzberg-Minder K., Ritzmann M., Fux R.
Microorganisms 2023,11,1675. https://doi.org/10.3390/microorganisms11071675 - MERS-CoV-Specific T-Cell Responses in Camels after Single MVA-MERS-S Vaccination.
Meyer Zu Natrup C, Schünemann LM, Saletti G, Clever S, Herder V, Joseph S, Rodriquez M, Wernery U, Sutter G, Volz A.
Emerg Infect Dis. 2023 Jun;29(6):1236-1239. doi: 10.3201/eid2906.230128. PMID: 37209676. - Recombinant Modiefied Vaccinia Virus Ankara Expressing a Glycosylation Mutant of Dengue Virus NS1 Induces Specific Antibody and T-Cell Responses in Mice.
Wilken L., Stelz S., Agac A., Sutter G., Prajeeth C.K., Rimmelzwaan G.F.
Vaccines (Basel) 2023 Mar 23;11(4):714. doi: 10.3390/vaccines11040714 - A recombinant Modified Vaccinia virus Ankara expressing prME of tick-borne encephalitis virus affords mice full protection against TBEV infection.
Kubinski M., Beicht J., Zdora I., Biermann J., Puff C., Gerlach T., Tscherne A., Baumgärtner W., Osterhaus A.D.M.E., Sutter G., Prajeeth C.K., Rimmelzwaan G.F.
Front Immunol. 2003 Apr 21;14:1182963. doi: 10.3389/fimmu.2023.1182963. eCollection 2023 - Improving poxvirus-mediated antitumor immune responses by deleting viral cGAMP-specific nuclease.
Riederer S., Canizo, A. del, Navas J., Peter M.G., Link E.K., Sutter G., Rojas J.J.
Cancer Gene Ther. 2023 Apr 4. doi: 10.1038/s41417-023-00610-5 - Der Huchen stirbt aus - was tun? Gefährdungsfaktoren und notwendige Maßnahmen in Bayern und Österreich.
Schmutz S., Jungwirth M., Ratschan C., Siemens S. von, Guttmann S., ..., Sutter G., Schröder W., Zauner G.
Österreichs Fischerei, 76. Jahrgang Sonderausgabe 2023, https://www.fischerei-verband.at/themen/fisch-des-jahres/2023-hucher/ - Brief Report: Monkeypox Virus Cross-Neutralizing Antibodies in Clinical Trial Subjects Vaccinated with Modified Vaccinia Virus Ankara Encoding MERS-Coronavirus Spike Protein.
Raadsen M.P., Dahlke C., Fathi A., Lamers M.M., Doel van den P., Zaeck L.M., Royen van M.E., Bruin de E., Sikkema R., Koopmans M., Gorp van E.C.M., Sutter G., Vries de R.D., Addo M.M., Haagmans B.L.
J Infect Dis. 2023 Mar 1;jiad052. https://doi.org/10.1093/infdis/jiad052 - Direct intranodal tonsil vacination with modified vaccinia Ankara vaccine protects macaques from highly pathogenic SIVmac 251.
Mattathil J.G., Volz A., Onabajo O.O., Maynard S., Bixler S.L., Shen X.X., Vargas-Inchaustegui D., Robert-Guroff M., Lebranche C., Tomaras G., Montefiori D., Sutter G., Mattapallil J.J.
Nat Commun. 2023 Mar 07;14(1):1264. https://doi.org/10.1038/s41467-023-36907-0 - Bacterial and Viral Pathogens with One Health Relevance in Invasive Raccoons (Procyon lotor, Linne 1758) in Southwest Germany.
Reinhardt N.P., Köster J., Thomas A., Arnold J., Fux R., Straubinger R.K.
Pathogens 2023 Mar 1;12(3):389. https://doi.org/10.3390/pathogens12030389 - Efficient stabilization of therapeutic hepatitis B vaccine components by amino-acid formulation maintains its potential to break immune tolerance.
Sacherl J., Kosinska A.D., Kemter K., Kächele M., Laumen C.S., Kerth H.A., Öz E.A., Wolff L.S., Su J., Essbauer S., Sutter G., Scholz M., Singethan K., Altrichter J., Protzer U.
JHEP Rep. 2023 Feb; 5(2):100603. doi: 10.1016/j.jhepr.2022.100603
2022
- Stabilized recombinant SARS-CoV-2 spike antigen enhances vaccine immmunogenicity and protective capacity.
Meyer zu Natrup C., Tscherne A., Dahlke C., Ciurkiewicz M., Shin D.-l., Fathi A., Rohde C., Kalodimou G., Halwe S., Limpinsel L., Schwarz J.H., Klug M., Esen M., Schneiderhan-Marra N., Dulovic A., Kupke A., Brosinski K, Clever S, Schünemann L.-M., Beythien G., Armando F., Mayer L., Weskamm L.M., Jany S., Freudenstein A., Tuchel T., Baumgärtner W., Kremsner P., Fendel R., Addo M.M., Becker S., Sutter G., Volz A.
J Clin Invest. 2022 Dez 15 132(24); e159895. doi: 10.1172/JCI159895. - Reproductive failure in an Austrian piglet-producing farm due to porcine circovirus genotype 2d.
Reif J., Renzhammer R., Brunthaler R., Weissenbacher-Lang C., Auer A., Kreutzmann H., Fux R., Ladinig A., Unterweger C.
Acta Vet Hung. 2022 Jun 21. doi: 10.1556/004.2022.00010 - Macrophages in dermal disease progression of phospholipase D4-deficient Fleckvieh calves.
Langenmayer M.C., Jung S., Fux R., Wittlinger C., Tschoner T., Majzoub-Altweck M., Knubben-Schweizer G., Fries R., Hermanns W., Trefz F.M.
Vet Pathol. 2022 Mar;59(2):319-327. doi: 10.1177/03009858211062629. Epub 2021 Dec 2.
- Persistence of MERS-CoV-spike-specific B cells and antibodies after late third immunization with the MVA-MERS-S vaccine.
Weskamm L.M., Fathi A., Raadsen M.P., ..., Sutter G., Dahlke C., Addo M.M.
Cell Rep Med. 2022 Jul 19;3(7):100685. https://doi.org/10.1016/j.xcrm.2022.100685 - Adaptation of Brucella melitensis Antimicrobial Susceptibility Testing to the ISO 20776 Standard and Validation of the Method.
Tscherne A., Mantel E., Boskani T., Budniak S., Elschner M., Fasanella A., Feruglio S.L., Galante D., Giske C.G., Grunow R., Henczko J., Hinz C., Iwaniak W., Jacob D., Kedrak-Jablonska A., Jensen V.K., Johansen T.B., Kahlmeter G., Manzulli V., Matuszek E., Melzer F., Nuncio M.S. Papaparaskevas J., Pelerito A., Solheim M., Thomann S., Tsakris A., Wahab T., Weiner M., Zoeller L., Zange S., EMERGE AST Working Group.
Microorganisms. 2022 Jul 20;10(7):1470. doi: 10.3390/microorganism10071470 - Increased neutralization and IgG epitope identification aftre MVA-MERS-S booster vaccination against Middle East respiratory syndrome.
Fathi A., Dahlke C., Krähling V., Kupke A., Okba N.M.A., Raadsen M.P., Heidepriem J., Müller M.A., Paris G., Lassen S., KLüver M., Volz A., Koch T., Ly M.L., Friedrich M., Fux R., Tscherne A., Kalodimou G., Schmiedel S., Corman V.M., Hesterkamp T., Drosten C., Loeffer F.F., Haagmans B.L., Sutter G., Becker S., Addo M.M.
Nature Communications 2022 Jul 19;13(1):4182. https://doi.org/10.1038/s4167-022-31557-0 - Cross-Sectional Study on the Prevalence of PCV Types 2 and 3 DNA in Suckling Piglets Compared to Grow-Finish Pigs in Downstream Production.
Eddicks M., Maurer R., Deffner P., Eddicks L., Sipos W., Reese S., Cvjetkovic V., Krejci R., Opriessnig T., Ritzmann M., Fux R.
Pathogens 2022 Jun 10;11(6):671. https://doi.org/10.3390/pathogens11060671 - Protective CD8+ T Cell Response Induced by Modified Vaccinia Virus Ankara Delivering Ebola Virus Nucleoprotein.
Kupke A., Volz A., Dietzel E., Freudenstein A., Schmidt J., Shams-Eldin H., Jany S., Sauerhering L., Krähling V., Serra M.G., Herden C., Eickmann M., Becker S., Sutter G.
Vaccines 2022 Mar 29;10(4):533. https://doi.org/10.3390/vaccines10040533 - Detection of DNA sequences attributed to bovine meat and milk factors (BMMF/SPHINX) in food-related samples.
Pohl S., Habermann D., Link E.K., Fux R., Boldt C.L., Franz C.M.A.P., Hölzel C., Klempt M.
Food Control 135 (2022) 108779. doi.org/10.1016/j.foodcont.2021.108779 - Detection of porcine circovirus type 3 DNA in serum and semen samples of boars from a German boar stud.
Eddicks M., Müller M., Fux R., Ritzmann M., Stadler J.
Vet J. 2022 Jan;279:105784. doi.org/10.1016/j.tvjl.2021.105784. Epub 2021 Dec.10.
2021
- Intranasal Delivery of MVA Vector Vaccine Induces Effective Pulmonary Immunity Against SARS-CoV-2 in Rodents.
Bosnjak B., Odak I., Barros-Martins J., Sandrock I., Hammerschmidt S.I., Permanyer M., Patzer G.E., Greorgiev H., Jauregui R.G., Tscherne A., Schwarz J.H., Kalodimou G., Ssebyatika G., Ciurkiewicz M., Willenzon S., Bubke A., Ristenpart J., Ritter C., Tuchel T., Meyer zu Natrup C., Shin D.-L., Clever S., Limpinsel L., Baumgärtner W., Krey T., Volz A., Sutter G., Förster R.
Frontiers in Immunology 2021 Nov 11, Vol. 12, Article 772240. doi: 10.3389/frmmu.2021.772240e.Collection 2021 - Identification and Characterization of Circular Single-Stranded DNA Genomes in Sheep and Goat Milk.
König M.-T., Fux R., Link E., Sutter G., Märtlbauer E., Didier A.
Viruses 2021, 13(11):2176. doi.org/10.3390/v13112176 - Activation of interferon regulatory factor 3 by raplication-competent vaccinia viruses improves antitumor efficacy mediated by T cell responses.
Riederer S., Fux R., Lehmann M.H., Volz A., Sutter G., Rojas J.J.
Molecular Therapy: Oncolytics 2021 Sep 24;22:399-409 - B cell depletion impairs vaccination-induced CD8+T cell responses in a type I interferon- dependent manner.
Graalmann T., Borst K., Manchanda H., Vaas L., et al.
Ann Rheum Dis. 2021 Dec; 80(12):1537-1544. doi:10.1136/annrheumdis-2021-220435 - Prolonged SARS-CoV-2 RNA Shedding from Therapy Cat after Cluster Outbreak in Retirement Home.
Schulz C., Wylezich C. Wernike K., Gründl M., Dangel A., et al.
Emerg Infect Dis. 2021 Jul:27(7):1974-1976. doi.org/10.3201/eid2707.204670 - Immunogenicity and efficacy of the COVID-19 candidate vector vaccine MVA-SARS-2-S in preclinical vaccination. (pdf, 1,36 MB + 1,46 MB)
Tscherne A., Schwarz J.H., Rohde C., Kupke A., Kalodimou G., Limpinsel L., Okba N.M.A., Bosnjak B., Sandrock I., Odak I., Halwe S., Sauerhering L., Brosinski K., Liangliang N., Duell E., Jany S., Freudenstein A., Schmidt J., Werner A., Serra M.G., Klüver M., Guggemos W., Seilmaier M., Wendtner C.-M., Förster R., Haagmans B.L., Becker S., Sutter G., Volz A.
Proc Natl Acad Sci USA 2021 Jul 13;118 e2026207118. doi.org/10.1073/pnas.2026207118 - Equine herpesvirus-1 Distribution in Equine Lymphoid and Neural Tissues 70 Days Post Infection.
Samoilowa S., Giessler K.S., Torres C.E.M., Hussey G.S., Allum A., Fux R., Jerke C., Kiupel M., Matiasek K., Sledge D.G., Goehring L.S.
Pathogens 2021 Jun 5;10(6):707. doi: 10.3390/pathogens 10060707 - Circular Rep-Encoding Single-Stranded DNA Sequences in MIlk from Water Buffaloes (Bubalus arnee f. bubalis).(pdf, 4,9 M)
König M.-T., Fux R., Link E., Sutter G., Märtlbauer E., Didier A.
Viruses 2021 Jun 7; 13(6):1088. doi:10.3390/v13061088 - Reconsideration of the diagnostic criteria required for PCV2 reproductive disease.
Unterweger C., Brunthaler R., Auer C., Fux R., Weissenbacher-Lang C., Ladinig A.
The Veterinary Journal 2021 Jun;272:105660.doi.org/10.1016/j.tvjl.2021.105660. Epub 2021 Mar 23. - Discriminating the eight genotypes of the porcine circovirus type 2 with TaqMan-based real-time PCR. (pdf, 2,65 MB)
Link E.K., Eddicks M., Nan L., Ritzmann M., Sutter G., Fux R.
Virology Journal, 2021 Apr 7;18(1):70. doi. 10.1186/s12985-021-01541-z
2020
- Phosphorylation Control of p53 DNA-Binding Cooperativity Balances Tumorigenesis and Aging.
Timofeev O., Koch L., Niederau C., Tscherne A., Schneikert J., Klimovich M., Elmshäuser S., Zeitlinger M., Mernberger M., Nist A., Osterburg C., Dötsch V., German Mouse Clinic Consortium, Hrabe de Angelis M., Stiewe T.
Cancer Res 2020 Dec 1;80(23):5231-5244. doi: 10.1158/0008-5472.CAN-20-2002. Epub 2020 Sep 1. - NOTIFy (non-toxic lyophilized field)-FISH for the identification of biological agents by Fluorescence in situ Hybridization.
Aistleitner K., Sieper T., Stürz I., Jeske R., Tritscheller S., Mantel S., Tscherne A., Zange S., Stoecker K., Wölfel R.
PLoS ONE. 2020 Mar 6;15(3):e0230057. doi: 10.1371/journal.pone.0230057.eCollection 2020. - Viral Load and Cell and Tropism During Early Latent Equid Herpesvirus 1 Infection Differ Over Time in Lymphoid and Neural Tissue Samples From Experimentally Infected Horses.
Giessler K.S., Samoilowa S., Hussey G.S., Kiupel M., Matiasek K., Sledge D.G., Liesche F., Schlegel J., Fux R., Goehring L.S.
Front Vet Sci. 2020 Sep 4;7:621. doi: 10.3389/fvets.2020.00621. eCollection 2020. - Recombinant viruses delivering the necroptosis mediator MLKL induce a potent antitumor immunity in mice. (pdf, 2,49 MB)
Van Hoecke L., Riederer S., Saelens X., Sutter G., Rojas J.J.
Oncolmmunology, 20 Aug 2020, 9:(1): e1802968, DOI: 10.1080/2162402X.2020.1802968 - Trick-Borne Encephalitis Virus: A Quest for Better Vaccines against a Virus on the Rise. (pdf, 1,45 MB)
Kubinski M., Beicht J., Gerlach T., Volz A., Sutter G., Rimmelzwaan G.F.
Vaccines (Basel). 2020;8(3):E451. Published 2020 Aug 12. doi:10.3390/vaccines8030451 - Combating COVID-19: MVA vector vaccines applied to the respiratory tract as promising approach toward protective immunity in the lung. (pdf, 294 KB)
Förster R., Fleige H., Sutter G.
Frontiers in Immunology, 2020, Aug 07; 11:1959. doi:3389/fmmu.2020.01959 - Diverse variola virus (smallpox) strains were widespread in northern Europe in the Viking Age. (pdf, 727 KB)
Mühlemann B., Vinner L., Margaryan A., Wilhelmson H., Castro C. de la Fuente, Allentoft M.E., Damgaard P. de Barros., Hansen A.J., Nielsen S.H., Strand L.M., Bill J., Buzhilova A., Pushkina T., Falys C., Khartanovich V., Moiseyev V., Jorkov M.L. Schjellerup, Sorensen P.O., Magnusson Y., Gustin I., Schroeder H., Sutter G., Smith G.L., Drosten C., Fouchier R.A.M., Smith D.J., Willerslev E., Jones T.C., Sikora M.
Science, 2020, July 24;369(6502):eaaw8977. DOI: 10.1126/science.aaw8977 - Salety and immnogenicity of a modified vaccinia virus Ankara vector vaccine candidate for Middle East respiratory syndrome: an open-label, phase 1 trial. (pdf, 1,42 MB)
Koch T., Dahlke C., Fathi A., Kupke A., Krähling V., Okba N.M.A., Halwe S., Rohde C., Eickmann M., Volz A., Hesterkamp T., Jambrecina A., Borregaard S., Ly M.L., Zinser M.E., Bartels E., Poetsch J.S.H., Neumann R., Fux R., Schmiedel S., Lohse A.W., Haagmans B.L., Sutter G., Becker S., Addo M.M.
Lancet Infect Dis, 2020, Jul; 20(7):827-838. doi:10.1016/S1473-3099(20)30248-6. Epub 2020 Apr 21 - A vital gene for modified vaccinia virus Ankara replication in human cells. (pdf, 621 KB)
Sutter G.
Proc Natl Acad Sci USA, 2020, Mar 24;117(12):6289-6291.doi/10.1073/pnas.2001335117, Epub.2020 Marz 16 - Selective reconstitution of IFN-y gene function in Ncr1+NK cells is sufficient to control systemic vacinia virus Infection. (pdf, 1,95 MB)
Borst K., Flindt S., Blank P., Larsen P.-K., Chhatbar C., Skerra J., Spanier J., Hirche C., König M., Alanentalo T., Hafner M., Waibler Z., Pfeffer K., Sexl V., Sutter G., Müller W., Graalmann T., Kalinke U.
PLoS Pathog, 2020, Feb 5;16(2):e1008279. doi:10.1371/jounal.ppat.1008279. eCollection 2020 Feb - Obstetric Ultrasonography to Detect Fetal Abnormalities in a Mouse Model for Zika Virus Infektion. (pdf, 2,96 MB)
Forster D., Schwarz J.H., Brosinski K., Kalinke U., Sutter G., Volz A.
Viruses, 2020, Jan 7;12(1):72. doi:10.3390/v12010072 - A Soluble Version of Nipah Virus Glycoprotein G Delivered by Vaccinia Virus MVA Activates Specific CD8 and CD4 T Cells in Mice. (pdf, 2,57 MB)
Kalodimou G., Veit S., Jany S., Kalinke U., Broder C.C., Sutter G., Volz A.
Viruses, 2020, 12, 26. doi.10.3390/v12010026 - Genotyping Porcine Circovirus 3 (PCV-3) Nowadays: Does It Make Sense? (pdf, 1,57 MB)
Franzo G., Delwart E., Fux F., Hause B., Su S., Zhou J., Segales J.
Viruses, 2020, 12, 265. doi:10.3390/v12030265
2019
- Evalution of in vitro antimicrobial susceptibility of Bacillus anthracis strains isolated during anthrax outbreaks in Italy from 1984 to 2017.
Manzulli V., Fasanella A., Parisi A., Serrecchia L., Donatiello A., Rondinone V., Caruso M., Zange S., Tscherne A., Decaro N., Pedarra C., Galante D.
J Vet Sci. 2019 Jan 31;20(1):58-62. doi. 10.4142/jvs.2019.20.1.58 - Proliferative kidney disease and proliferative darkening syndrome are linked with brown trout (Salmo trutta fario) mortalities in the pre-alpine Isar River.
(pdf, 13,785 KB)
Arndt D., Fux R., Blutke A., Schwaiger J., El-Matbouli M., Sutter G.,
Langenmayer M.C.
Pathogens, 2019 Oct 6;8(4). pii: E177. doi: 10.3390/pathogens8040177 - Piscine orthoreovirus 3 is not the causative pathogen of proliferative darkening syndrome (PDS) of brown trout (Salmo trutta fario). (pdf, 2,631 KB)
Fux R., Arndt D., Langenmayer M.C., Schwaiger J., Ferling H., Fischer N., Indenbirken D., Grundhoff A., Dölken L., Adamek M., Steinhagen D., Sutter G.
Viruses, 2019 Jan 28;11(2). pii: E112. doi:10.3390/v11020112
2018
- CD8+ T cells responding to the Middle East respiratory syndrome coronavirus nucleocapsid protein delivered by vaccinia virus MVA in mice. (pdf, 2,035 KB)
Veit S., Jany S., Fux R., Sutter G., Volz A.
Viruses 2018, 10(12), 718; doi:103390/v10120718 - Cross-sectional study on viraemia and shedding of porcine circovirus type 2 in a subclinically infected multiplier sow herd. (pdf, 244 KB)
Eddicks M., Beuter B., Stuhldreier R., Nolte T., Reese N., Sutter G., Ritzmann M., Fux R.
Veterinary Rec., 2018 Nov 09, doi:10.1136/vr.105069 - Generation of therapeutic antisera for emerging viral infections. (pdf, 1,600 KB)
Schmidt R., Beltzig L.C., Sawatsky B., Dolnik O., Dietzel E., Krähling V., Volz A., Sutter G., Becker S., von Messling V.
NPJ Vaccines, 2018 Oct 5, 3:42 doi:10.1038/s41541-018-0082-4. eCollection 2018 - N-terminal domain of Schmallenberg virus envelope protein Gc delivered by recombinant equine herpesvirus type 1 and modified vaccinia virus Ankara: Immunogenicity and protective efficacy in cattle. (pdf, 1,661 KB)
Wernike K., Mundt A., Link E.K., Aebischer A., Schlotthauer F., Sutter G., Fux R., Beer M.
Vaccine, 36(34), 5116-5123 (2018) - Immunogenic cell death of dendritic cells following modified vaccinia virus Ankara infection enhances CD8+ T cell proliferation. (pdf, 1,750 KB)
Tappe K.A., Budida R., Stankov M.V., Frenz T., Shah H., Volz A., Sutter G., Kalinke U., Behrens G.M.N.
Eur. J. Immunol., 48(12), 2042-2054 (2018) - Tracking Modified Vaccinia Virus Ankara in the Chicken Embryo: In Vivo Tropism and Pathogenesis of Egg Infections. (pdf, 1,755 KB)
Langenmayer M., Lülf-Averhoff A.-T., Adam-Neumair S., Sutter G., Volz A.
Viruses, 10(9), pii: E452 (2018), doi:10.3390/ v10090452 - Induction of Cross-Clade Antibody and T-Cell Responses by a Modified Vaccinia Virus Ankara-Based Influenza A(H5N1) Vaccine in a Randomized Phase 1/2a Clinical Trial. (pdf, 2,49 MB)
de Vries R.D., Altenburg A.F., Nieuwkoop N.J., de Bruin E., van Trierum S.E., Pronk M.R., Lamers M.M., Richard M., Nieuwenhuijse D.F., Koopmans M.P.G., Kreijtz J.H.C.M., Fouchier R.A.M., Osterhaus A.D.M.E., Sutter G., Rimmelzwaan G.F.
J. Infect. Dis., 218(4), 614-623 (2018) - Porzines Circovirus Typ 3-ein "emerging Pathogen"?
Eddicks M., Fux R.
Der Prakt. Tierarzt, 99(06), 604-605 (2018) - Distribution and absence of generalized lesions in mice following single dose intramuscular inoculation of the vaccine candidate MVA-MERS-S. (pdf, 1,39 MB)
Langenmayer M.C., Lülf-Averhoff A.T., Adam-Neumair S., Fux R., Sutter G., Volz A.
Biologicals, 54, 58-62 (2018) - Manifold Roles of CCR7 and Its Ligands in the Induction and Maintenance of Bronchus-Associated Lymphoid Tissue. (pdf, 7,13 MB)
Fleige H., Bosnjak B., Permanyer M., Ristenpart J., Bubke A., Willenzon S., Sutter G., Luther S.A., Förster R.
Cell Rep, 23(3), 783-795 (2018) - Applicationn of light sheet microscopy for qualitative and quantitative analysis of bronchus-associated lymphoid tissue in mice. (pdf, 7,03 MB)
Mzinza D.T., Fleige H., Laarmann K., Willenzon S., Ristenpart J., Spanier J., Sutter G., Kalinke U., Valentin-Weigand P., Förster R.
Cell Mol. Immunol., 15(10):875-887 (2018) - Full genome characterization of porcine circovirus type 3 isolates reveals the existence of two distinct groups of virus strains. (pdf, 1,03 MB)
Fux R., Söckler C., Link E.K., Renken C., Krejci R., Sutter G., Ritzmann M., Eddicks M.
Virology Journal, 15(1), Art. Nr. 25 (2018) doi:10.1186/s12985-018-0929-3 - Investigation of three outbreaks of Porcine Epidemic Diarrhea in Germany in 2016 demonstrates age dependent differences in the development of humoral immune response. (pdf, 486 KB)
Stadler J., Moser L., Numberger J., Rieger A., Strutzberg-Minder K., Stellberger T., Ladinig A., Ritzmann M., Fux R.
Preventive Veterinary Medicine, 150, 93-100 (2018)
- E3L and F1L gene functions modulate the protective capacity of modified vaccinia virus Ankara immunization in murine model of human smallpox. (pdf, 1,221 KB)
Volz A., Jany S., Freudenstein A., Lantermann M., Ludwig H., Sutter G.
Viruses, 10(1), pii: E 21 (2018) - Type I interferon receptor-signaling delays Kupffer cell replenishment during acute fulminant viral hepatitis. (pdf, 6,58 MB)
Borst K., Frenz T., Spanier J., Tegtmeyer P.K., Chhatbar C., Skerra J., Ghita L., Namineni S., Lienenklaus S., Köster M., Heikenwaelder M., Sutter G., Kalinke U.
J. Hepatol., 68(4), 682-690 (2018)
2017
- Modified Vaccinia Virus Ankara Preferentially Targets Antigen Presenting Cells In Vitro, Ex Vivo and In Vivo. (pdf, 8,35 MB)
Altenburg A.F., Sandt C.E. van de, Li B.W.S., MacLoughlin R.J., Fouchier R.A.M., Amerongen G. van, Volz A., Hendriks R.W., Swart R.L. de, Sutter G., Rimmelzwaan G.F., Vries R.D. de.
Sci. Rep., 7(1), Art. Nr. 8580 (2017) doi:10.1038/s41598-017-08719-y - Sus scrofa papillomavirus 2 - genetic characterization of a novel suid papillomavirus from wild boar in Germany. (pdf, 786 KB)
Link E.K., Hoferer M., Strobel B., Rigbers K., Langenmayer M.C., Sutter G., Fux R.
J. Gen. Virol., 98(8), 2113-2117 (2017) - A synthetic human cytomegalovirus pp65-IE1 fusion antigen efficiently induces and expands virus specific T cells. (pdf, 1,89 MB)
Link E.K., Brandmüller C., Suezer Y., Ameres S., Volz A., Moosmann A., Sutter G., Lehmann M.H.
Vaccine, 35(38), 5131-5139 (2017) - The Munich MIDY Pig Biobank - A unique resource for studying organ crosstalk in diabetes.
Blutke A., Renner S., Flenkenthaler F., Backman M., Haesner S., Kemter E., Ländström E., Braun-Reichhart C., Albi B., Streckel E., Rathkolb B., Prehn C., Palladini A., Grzybek M., Krebs S., Bauersachs S., Bähr A., Brühschwein A., Deeg C.A., De Monte E., Dmochewitz M., Eberle C., Emrich D., Fux R., Groth F., Gumbert S., Heitmann A., Hinrichs A., Keßler B., Kurome M., Leipig-Rudolph M., Matiasek K., Öztürk H., Otzdorff C., Reichenbach M., Reichenbach H.D., Rieger A., Rieseberg B., Rosati M., Saucedo M.N., Schleicher A., Schneider M.R., Simmet K., Steinmetz J., Übel N., Zehetmaier P., Jung A., Adamski J., Coskum Ü., Hrabe de Angelis M., Simmet C., Ritzmann M., Meyer-Lindenberg A., Blum H., Arnold G.J., Fröhlich T., Wanke R., Wolf E.
Molecular Metabolism, 6(8), 931-940 (2017) - Porcine Epidemic Diarrhea in Europe: In-Detail Analyses of Disease Dynamics and Molecular Epidemiology.
Hanke D., Pohlmann A., Sauter-Louis C., Höper D., Stadler J., Ritzmann M., Steinrigl A., Schwarz B.-A., Akimkin V., Fux R., Blome S., Beer M.
Viruses, 9(7), E177 (2017) doi:10.3390/v9070177 - Porzine Circoviren - ein Update.
Eddicks M., Fux R.
Der Praktische Tierarzt, 98(4), 357-366 (2017) - Qualitative differences in cellular immunogenicity elicited by hepatitis C virus T-Cell vaccines employing prime-boost regimens. (pdf, 5,6 M)
Tan W.G., Zubkova I., Kachko A., Wells F., Adler H., Sutter G., Major M.E.
PLoS ONE 12(7):e0181578 (2017) - Ectromelia virus accumulates less double-stranded RNA compared to vaccinia virus in BS-C-1 cells. (pdf, 1,56 MB)
Frey T.R., Lehmann H.M., Ryan C.M., Pizzorno, M.C., Sutter G., Hersperger A.R.
Virology 509, 98-111 (2017) - Vorkommen von Genotypen des porzinen Circovirus Typ 2 (PCV2) in Schweinebeständen mit unterschiedlichen Impfstrategien gegen PCV2. [Occurrence of genotypes of porcine circovirus (PCV2) in pig farms using different vaccination strategies against PCV2]. (pdf, 412 KB)
Eddicks M., Szikora F., Walhöfer N., Sauer-Louis C., Reese S., Banholzer E., Reiner G., Sutter G., Ritzmann M., Fux R.
Tierärztl. Prax., Ausg.(G), 45(2), 90-97 (2017) - Editorial overview: Preventive and therapeutic vaccines: Vaccination against viral disease - current advances and challenges. (pdf, 141 KB)
Rappuoli R., Sutter G.
Curr. Opin. Virol., 23, vi-viii (2017) - Comparison of real-time reverse transcriptase polymerase chain reaction of peripheral blood mononuclear cells, serum and cell-free body cavity effusion for the diagnosis of feline infectious peritonitis. (pdf, 6,54 MB)
Doenges S.J., Weber K., Dorsch R., Fux R., Hartmann K.
J. Feline Med. Surg., 19(4), 344-350 (2017)
- Modified Vaccinia virus Ankara: History, value in basic research, and current perspectives for vaccine development. (pdf, 11 MB)
Volz A., Sutter G.
Advances in Virus Res., 97, 187-243 (2017)
2016
- Porzine Circovirus Typ 2 (PCV2) - Infektionen in oberbayerischen Schweinemastbeständen mit routinemäßiger Impfung gegen PCV2. -Bedeutung für das Auftreten von Lungenveränderungen bei Schlachttierkörpern-.
Nicoll I., Striegl J., Fux R., Sutter G., Ritzmann M., Eddicks M.
Tierärztl. Umschau, 71(10), 360-370 (2016) - Non-plaque-forming virions of Modified Vaccinia virus Ankara express viral genes. (pdf, 843 KB)
Lülf A.T., Freudenstein A., Marr L., Sutter G., Volz A.
Virology, 499, 322-330 (2016) - Increased protein degradation improves influenza Virus nucleoprotein-specific CD8+ T cell activation in vitro but not in C57BL/6 mice. (pdf, 1,83 MB)
Altenburg A.F., Sandt C.E. van de, Trierum S.E. van, Gruyter H.L. De, Run P.R. van, Fouchier R.A., Roose K., Saelens X., Volz A., Sutter G., Vries R.D. de,
Rimmelzwaan G.F.
J. Virol., 90(22), 10209-10219 (2016) - Anti-apoptotic Bcl-XL but not Mcl-1 contributes to protection against virus-induced apoptosis. (pdf, 702 KB)
Ohmer M., Weber A., Sutter G., Ehrhardt K., Zimmermann A., Häcker G.
Cell Death Dis., 7(8):e2340 (2016)
doi: 10.1038/cddis.2016.242. - T-and B-cell responses to multivalent prime-boost DNA and viral vectored vaccine combinations against hepatitis C virus in non-human primates. (pdf, 1,06 MB)
Rollier C.S., Verschoor E.J., Verstrepen B.E., Drexhage J.A., Paranhos-Baccala G., Liljeström P., Sutter G., Arribillaga L., Lasarte J.J., Bartosch B., Cosset F.L., Inchauspe G., Heeney J.L.
Gene Ther., 23(10), 753-759 (2016) - Low pathogenic avian influenza (H9N2) in chicken: Evaluation of an ancestral H9-MVA vaccine. (pdf, 1,03 MB)
Ducatez M., Becker J., Freudenstein A., Delverdier M., Delpont M., Sutter G., Guerin J.-L., Volz A.
Vet. Microbiol., 189, 59-67 (2016) - Low prevalence of porcine circovirus type 2 infections in farrowing sows and corresponding pre-suckling piglets in southern German pig farms. (pdf, 485 KB)
Eddicks M., Koeppen M., Willi S., Fux R., Reese S., Sutter G., Stadler J.,
Ritzmann M.
Vet. Microbiol., 187, 70-74, (2016) - CCL2 expression is mediated by type I IFN receptor and recruits NK and T cells to the lung during MVA infection. (pdf, 1,26 MB)
Lehmann M.H., Torres-Dominquez L.E., Price P.J.R., Brandmüller C., Kirschning C.J., Sutter G.
J. Leukoc. Biol., Vol. 99(6), 1057-1064 (2016) - Immunogenicity and protective efficacy of recombinant Modified Vaccinia virus Ankara candidate vaccines delivering West Nile virus envelope antigens.
(pdf, 1,75 MB)
Volz A., Lim S., Kaserer M., Lülf A., Marr L., Jany S., Deeg C.A., Pijlman G.P.,
Koraka P., Osterhaus A.D., Martina B.E., Sutter G.
Vaccine, 34(16), 1915-1926 (2016) - Myristoylation increases the CD8+ T cell response to a GFP prototype antigen delivered by modified vaccinia virus Ankara. (pdf, 1,05 MB)
Marr L., Lülf A.T., Freundenstein A., Sutter G., Volz A.
J. Gen. Virol., 97(4), 934-940 (2016) - Rusa alfredi papillomavirus 1 -a novel deltapapillomavirus inducing endemic papillomatosis i the endangered Visayan spotted deer. (pdf, 4,18 MB)
Fux R., Langenmayer M.C., Jörgens D., Schubert C., Heckel J-O., Sutter G.
J. Gen. Virol., 97(1), 128-133 (2016) - In Vivo Killing Capacity of Cytotoxic T Cells Is Limited and Involves Dynamic Interactions and T Cell Cooperativity. (pdf, 3,77 MB)
Halle S., Keyser K.A., Stahl F.R., ..., Sutter G., Messerle M., Förster R.
Immunity, 44(2), 233-245 (2016) - Detection of feline coronavirus in cerebrospinal fluid for diagnosis of feline infectious peritonitis in cats with and without neurological sings. (pdf, 669 KB)
Doenges S.J., Weber K., Dorsch R., Fux R., Fischer A., Matiasek L.A., Matiasek K., Hartmann K.
J. Feline Medicine Surgery, 18(2), 104-109 (2016) - An orthopoxvirus-based vaccine reduces virus excretion after MERS-CoV infection in dromedary camels. (pdf, 12,3 MB)
Haagmans B.L., Brand J.M.A. van den, Raj S.V., Volz A., Wohlsein P., Smits S.L., Schipper D., Bestebroer T.M., Okba N., Fux R., Bensaid A., Selanes Foz D.S., Kuiken T., Baumgärtner W., Segales J., Sutter G., Osterhaus A.D.M.E.
Science, 351(6268), 77-81 (2016)
2015
- Modifiziertes Vacciniavirus Ankara (MVA) - die Entwicklung als Vektorimpfstoff und Einsatzmöglichkeiten in der Veterinärmedizin. (pdf, 1,43 MB)
Volz A., Fux R., Langenmayer M.C., Sutter G.
Berl. Münch. Tierärztl. Wochenschr., 128(11/12), 464-472 (2015) - Protective efficacy of recombinant Modified Vaccinia vurus Ankara delivering Middle East respiratory syndrome coronavirus spike glycoprotein. (pdf, 1,84 MB)
Volz A., Kupke A., Song F., Jany S., Fux R., Shams-Eldin H., Schmidt J., Becker C., Eickmann M., Becker S., Sutter G.
J. Virol., 89(19), 8651-8656 (2015) - Induction of influenza (H5N8) antibodies by modified vaccinia virus Ankara H5N1 vaccine. (pdf, 470 KB)
Vries R.D. de, Gruyter H.L.M. De, Bestebroer T.M., Pronk M., Fouchier R.A.M., Osterhaus A.D.M.E., Sutter G., Kreijtz J.H.C.M., Rimmelzwaan G.F.
Emerg. Infect. Dis., 21(6), 1086-1088 (2015) - Use of the LC16m8 smallpox Vaccine in immunocompromised individuals is still too risky. (pdf, 100 KB)
Danon Y.L., Sutter G.
Clin. Vaccine Immunol., 22(5), 604 (2015) - Detection of a new cluster of porcine circovirus type 2b strains in domestic pigs in Germany. (pdf, 4,92 MB)
Eddicks M., Fux R., Szikora F., Eddicks L., Majzoub-Altweck M., Hermanns W., Sutter G., Palzer A., Banholzer E., Ritzmann M.
Vet. Microbiol., 176(3-4), 337-343 (2015) - Modified vaccinia virus Ankara but not vaccinia virus induces chemokine expression in cells of the monocyte/macrophage lineage. (pdf, 992 KB)
Lehmann M.H., Price P.J.R., Brandmüller C., Sutter G.
Virology J., 12, 21 (2015) - Complement component C5 recruits neutrophils in the absence of C3 during respiratory infection with modified vaccinia virus Ankara. (pdf, 389 KB)
Price P.J.R., Banki Z., Scheideler A., Stoiber H., Verschoor A., Sutter G.,
Lehmann M.H.
J. Immunol., 194(3), 1164-1168 (2015) - A single immunization with an MVA-based influenza virus H7 vaccine affords protection in the H7N9 pneumonia ferret model. (pdf, 705 KB)
Kreijtz J.H.C.M., Wiersma L.C.M., Gruyter H.L.M. De, Vogelzang-van Trierum S.E., Amerongen G. van, Stittelaar K.J., Fouchier R.A.M., Osterhaus A.D.M.E., Sutter G., Rimmelzwaan G.F.J.
Infect. Dis., 211(5), 791-800 (2015)
2014
- Safety and immunogenicity of a modified-vaccinia-virus-Ankara-based influeza A H5N1 vaccine: a randomised, double-blind phase 1/2a clinical trial. (pdf, 276 KB)
Kreijtz J.H.C.M., Goeijenbier M., Moesker F.M., Dries L. van den, Goeijenbier S., Gruyter H.L.M. De, Lehmann M.H., Mutsert G. de, Vijver D.A.M.C. van de, Volz A., Fouchier R.A.M., Gorp E.C.M. van, Rimmelzwaan G.F., Sutter G., Osterhaus A.D.M.E.
Lancet Infect. Dis., 14(12), 1196-1207 (2014) - Prevalence of canine influenza virus A (H3N8) in dogs in Germany. (pdf, 180 KB)
Schulz B., Klinkenberg C., Fux R., Anderson T., Benedictis P. de, Hartmann K.
Veterinary Journal, 202(1), 184-185, (2014) - Recombinant modified vaccinia virus Ankara expressing glycoprotein E2 of Chikungunya virus protects AG129 mice against lethal challenge. (pdf, 1,71 MB)
Doel P. van den, Volz A., Roose J.M., Sewbalaksing V.D., Pijlman G.P., Middelkoop I. van, Duiverman V., Wetering E. van de, Sutter G., Osterhaus A.D.M.E., Byron M.E.E.
PLOS Neglected Tropical Diseases, 8(9), e3101 (2014) - Modified vaccinia virus Ankara (MVA) as production platform for vaccines against influenza and other viral respiratory diseases. (pdf, 817 KB)
Altenburg A.F., Kreijtz J.H.C.M., Vries R.D. de, Song F., Fux R., Rimmelzwaan G.F., Sutter G., Volz A.
Viruses, 6(7), 2735-2761 (2014) - Rapid expansion of CD8+ T cells in wild-type and type I interferon receptor deficient mice correlates with protection after low-dose emergency immunization with modified vaccinia virus Ankara. (pdf, 5,22 MB)
Volz A., Langenmayer M., Jany S., Kalinke U., Sutter G.
J. Virol., 88(18), 10946-10957 (2014) - Chemokine (C-C motif) receptor 1 Is required for efficient recruitment of neutrophils during respiratory infection with modified vaccinia virus Ankara.
(pdf, 2,96 MB)
Price P.J.R., Luckow B., Torres-Dominquez L.E., Brandmüller C., Zorn J., Kirschning C.J., Sutter G., Lehmann M.H.
J. Virol., 88(18), 10840-10850 (2014) - IL-17-induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCs. (pdf, 2,17 MB)
Fleige H., Ravens S., Moschovakis G.L., Bölter J., Willenzon S., Sutter G., Häussler S., Kalinke U., Prinz I., Förster R.
J. Exp. Med., 211(4), 643-651 (2014)
2013
- Middle east respiratory syndrome Coronavirus spike protein delivered by modified vaccinia virus Ankara efficiently induces virus-neutralizing antibodies.
(pdf, 155 KB)
Song F., Fux R., Provacia L.B., Volz A., Eickmann M., Becker S., Osterhaus A.D.M.E., Haagmans B.L., Sutter G.
Journal of Virology, 87(21), 11950-11954 (2013) - Vaccination with recombinant modified vaccinia virus Ankara prevents the onset of intestinal allergy in mice. (pdf, 835 K)
Bohnen C., Wangorsch A., Schülke S., Nakajima-Adachi H., Hachimura S., Burggraf M., Süzer Y., Schwantes A., Sutter G., Waibler Z., Reese G., Toda M., Scheurer S., Vieths S.
Allergy, 68(8), 1021-1028 (2013) - Poxvirus vectors. (pdf, 152 KB)
Kreijtz, J.H., Gilbert S.C., Sutter G.
Vaccine, 31(39), 4217-4219 (2013) - Adenoviral gizzard erosion in broiler chickens in Germany. (online abstract)
Schade B., Schmitt F., Böhm B., Alex M., Fux R., Cattoli G., Terregino C., Monne I., Currie R.J.W., Olias P.
Avian Diseases, 57(1), 159-163 (2013) - Protective efficacy of modified vaccinia virus Ankara in preclinical studies.
(pdf, 269 KB)
Volz A., Sutter G.
Vaccine, 31(39), 4235-4240 (2013) - Modified vaccinia virus Ankara: Innate immune activation and induction of cellular signalling. (pdf, 257 KB)
Price P.J.R., Torres-Dominquez L.E., Brandmüller C., Sutter, G., Lehmann M.H.
Vaccine, 31(39), 4231-4234 (2013) - Interleukin-1beta receptor expressed by modified vaccinia virus Ankara interferes with interleukin-1beta activity produced in various virus-infected antigen-presenting cells. (pdf, 450 KB)
Zimmerling S., Waibler Z., Resch T., Sutter G., Schwantes A.
Virol. J., 10(1) 34 (2013)
2012
- Transient elimination of circulating bovine viral diarrhoea virus by colostral antibodies in persistently infected calves: a pitfall for BVDV-eradication programs? (pdf, 521 KB)
Fux R., Wolf G.
Veterinary Microbiology, 161(1-2), 13-19 (2012) - Easy and efficient protocols for working with recombinant vaccinia virus MVA. (online-abstract)
Kremer M., Volz A., Kreijtz J.H., Fux R., Lehmann M.H., Sutter G.
Methods Mol. Biol., 890, 59-92 (2012) - Critical role of perforin-dependent CD8+ T cell immunity for rapid protective vaccination in a murine model for human smallpox. (pdf, 2,1 MB)
Kremer M.*, Suezer Y.*, Volz A.*, Frenz T., Majzoub M., Hanschmann K.-M., Lehmann M.H., Kalinke U., Sutter G.
PLoS Pathogens, 8(3), e1002557 (2012); *equal contribution - Modified vaccinia virus Ankara delivers a robust surrogate marker for immune monitoring to sarcoma cells even if cells are being exposed to chemotherapy and heat treatment. (pdf, 796 KB)
Tschoep-Lechner K., Drexler I., Hammer D., Neumann D., Pohla H., Sutter G., Noessner E., Issels R.-D.
Int. J. Hyperthermia, 28(1), 33-42 (2012) - Cytosolic DNA triggers mitochondrial apoptosis via DNA damage signaling proteins independently of AIM2 and RNA polymerase III. (pdf, 225 KB)
Wenzel M., Wunderlich M., Besch R., Poeck H., Willms S., Schwantes A., Kremer M., Sutter G., Endres S., Schmidt A., Rothenfusser S.
J. Immunology, 188(1), 394-403 (2012) - Pockenviren.Sutter G.In: Medizinische Mikrobiologie und Infektiologie. Hrsg. Suerbaum S., Hahn H., Burchard G.-D., Kaufmann S.H.E., Schulz T.F., Springer Verlag, 580-584 (2012)
2011
-
Preclinical evaluation of influenza vaccines based on replication-deficient poxvirus vector MVA. (pdf, 140 K)
Rimmelzwaan G.F., Kreijtz J.H.C.M., Suezer Y., Schwantes A., Osterhaus A.D.M.E., Sutter, G.
Procedia in Vaccinology, 4, 78-83 (2011) -
Induction of Noxa-mediated apoptosis by modified vaccinia virus Ankara depends on viral recognition by cytosolic helicases, leading to IRF-3/IFN-ß-dependent induction of pro-apoptotic Noxa. (pdf, 841 KB)
Ferrer P.E, Potthoff S., Kirschnek S., Gasteiger G., Kastenmüller W., Ludwig H., Paschen S.A., Villunger A., Sutter G., Drexler I., Häcker G.
PLoS Pathogens, 7(6), e1002083 (2011) -
HIV-1 Nef increases astrocyte sensitivity towards exogenous hydrogen peroxide. (pdf, 628 KB)
Masanetz S., Lehmann MH.
Virol. J., 8, 35 (2011) -
N1L is an ectromelia virus virulence factor and essential for in vivo spread upon respiratory infection. (pdf 3,1 M)
Gratz M.S., Suezer Y., Kremer M., Volz A., Majzoub M., Hanschmann K.-M., Kalinke U., Schwantes A., Sutter G.
J. Virol., 85(7), 3557-3569 (2011) - Uptake of antigens from modified vaccinia Ankara virus-infected leukocytes enhances the immunostimulatory capacity of dendritic cells. (online-abstract)
Flechsig C., Suezer Y., Kapp M., Tan S.M., Löffler J., Sutter G., Einsele H.,
Grigoleit G.U.
Cytotherapy, 13(6), 739-752 (2011)
2010
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Modified vaccinia virus Ankara (MVA) based vaccines-immunostimulatory and protective capacity.
Lehmann M.H., Kremer M., Suezer Y., Sutter G.
In: The Challenge of Highly Pathogenic Microorganisms - Mechanisms of Virulence and Novel Medical Countermeasures. Eds. Shafferman A., Ordentlich A., Velan B., Springer, 245-251 (2010) -
Evaluation of a modified vaccinia virus Ankara (MVA)-based candidate pandemic influenza A/H1N1 vaccine in the ferret model. (online-abstract)
Kreijtz J., Suezer Y., Bodewes R., Schwantes A., van Amerong G., Verburgh J. R., de Mutsert G., van den Brand J., van Trierum E.St., Kuiken T., Fouchier M.A.R., Osterhaus A., Sutter G., Rimmelzwaan F.
J. Gen. Virol., 91, 2745-2752 (2010) -
Concomitant type I IFN receptor-triggering of T cells and of DC is required to promote maximal modified vaccinia virus Ankara-induced T-cell expansion.
(online-abstract)
Frenz T., Waibler Z., Hofmann J., Hamdorf M., Lantermann M., Reizis B., Tovey G.M., Aichele P., Sutter G., Kalinke U.
Eur. J. Immunol., 40, 2769-2777 (2010) -
Functional F11L and K1L genes in modified vaccinia virus Ankara restore virus-induced cell motility but not growth in human and murine cells. (online-abstract)
Zwilling J., Sliva K., Schwantes A., Schnierle B., Sutter G.
Virology, 404, 231-239 (2010) -
Uncovering the interplay between CD8, CD4 and antibody responses to complex pathogens. (online-abstract)
Moutaftsi M., Tscharke C.D., Vaughan K., Koelle M.D., Stern L., Calvo-Calle M., Ennis F., Terajima M., Sutter G., Crotty S., Drexler I., Franchini G., Yewdell W.J., Head R.S., Blum J., Peters B., Sette A.
Future Microbiol., 5, 221-239 (2010) -
Viral host range factors C7 or K1 are essential for modified vaccinia virus Ankara late gene expression in human and murine cells, irrespective of their capacity to inhibit PKR-mediated elF2-a phosphorylation. (pdf, 696 KB)
Backes S., Sperling K., Zwilling J., Gasteiger G., Ludwig H., Kremmer E., Schwantes A., Staib C., Sutter G.
J. Gen. Virol., 91, 470-482 (2010) -
Pockenviren.
Schwantes A., Süzer Y., Sutter, G.
In: Medizinische Virologie. Hrsg. Doerr H.W., Gerlich W.H., Georg Thieme Verlag, 699-706 (2010)
2009
- Induced bronchus-associated lymphoid tissue serves as a general priming site for T cells and is maintained by dendritic cells. (pdf, 7,16 MB)
Halle St., Dujardin C.H., Bakocevic N., Fleige H., Danzer H., Willenzon St., Suezer Y., Hämmerling G., Garbi N., Sutter G., Worbs T., Förster R.
J. Exp. Med., 12, 2593-2601(2009) - Postexposure immunization with modified vaccinia virus Ankara or conventional Lister vaccine provides solid protection in a murine model of human smallpox. (pdf, 570 KB)
Paran N, Suezer Y., Lustig S., Israely T., Schwantes A., Melamed S., Katz L., Preuss T., Hanschmann K.M., Kalinke U., Erez N., Levin R., Velan B., Löwer J., Shafferman A., Sutter G.
J Infect Dis. 2009 Jan 1,199(1):39-48. doi:10.1086/595565 -
Smallpox vaccines – new formulations and revised strategies for vaccination.
(pdf, 711 KB)
Paran N., Sutter G.
Hum. Vaccines, 5(12), 824-831 (2009) -
MVA-based H5N1 vaccine affords cross-clade protection in mice against influenza A/H5N1 viruses at low doses and after single immunization. (pdf, 899 KB)
Kreijtz J., Suezer Y., de Mutsert G., van Amerongen G., Schwantes A., Fouchier R., Löwer J., Osterhaus A., Sutter G., Rimmelzwaan G.
PLoS ONE, e7790 (2009) -
Preclinical evaluation of a modified vaccinia virus Ankara (MVA)-based vaccine against influenza A/H5N1 viruses. (online-abstract)
Kreijtz J., Suezer Y., de Mutsert G., van den Brand J., van Amerongen G., Schnierle B.S., Kuiken T., Fouchier R., Löwer J., Osterhaus A., Sutter G., Rimmelzwaan G.
Vaccine, 27, 6296-6299 (2009) -
The orthopoxvirus 68k ankyrin-like protein is essential for DNA replication and complete gene expression of modified vaccinia virus Ankara in non-permissive human and murine cells. (pdf, 1,25 MB)
Sperling K.M., Schwantes A., Staib C., Schnierle B.S., Sutter G.
J. Virol., 83, 6029-6038 (2009) -
Candidate influenza vaccines based on recombinant modified vaccinia virus Ankara. (online-abstract)
Rimmelzwaan G., Sutter G.
Expert Rev. Vaccines, 8, 447-454 (2009) - An IFN-y-induced IRF-1-dependent antiviral response inhibits vaccinia virus replication in mouse but not human fibroblasts. (pdf, 1,71 MB)
Trilling M., Le V.T.K., Zimmermann A., Ludwig H., Pfeffer K., Sutter G., Smith G.L., Hengel H.
J. Virol., 83(8), 3684-3695 (2009) - Modified vaccinia virus Ankara (MVA) triggers chemotaxis of monocytes and early respiratory immigration of leukocytes by induction of CCL2 expression.
(pdf, 3,17 MB)
Lehmann M.H., Kastenmüller W., Kademir J.D., Brandt F., Suezer Y., Sutter G.
J. Virol., 83, 2540-2552 (2009) - Marker gene swapping facilitates recombinant Modified Vaccinia Ankara production by host-range selection. (online-abstract)
Di Lullo G., Soprana E., Panigada M., Palini A., Erfle V., Staib C., Sutter G.,
Siccardi A.G.
J. Virol. Methods, 156, 37-43 (2009) - Recombinant modified vacccinia Ankara expressing the hemaglutinin gene confers protection against homologous and heterologous H5N1 influenza virus infections in macaques. (pdf, 595 KB)
Kreijtz J., Suezer Y., de Mutsert G., van den Brand J.M., van Amerongen G., Schnierle B.S., Kuiken T., Fouchier R.A., Löwer J., Osterhaus A.D., Sutter G., Rimmelzwaan G.F.
J. Infect. Dis., 199, 405-413 (2009) -
Vaccinia virus-mediated inhibition of type I interferon responses is a multi-factorial process involving the soluble type I interferon receptor B18 and intracellular components. (pdf, 552 KB)
Waibler Z., Anzaghe M., Frenz T., Schwantes A., Pöhlmann C., Ludwig H., Palomo-Otero M., Alcami A., Sutter G., Kalinke U.
J. Virol., 83, 1563-1571 (2009)